Medicines

Here you will find the recommendations we have made about the use of individual medicines in Lancashire.

Canagliflozin

Brand: Invokana®
NICE TA: 315
Indication: In combination therapy for treating type 2 diabetes (NICE TA315)
Disease category: Endocrine system
Commissioning responsibility: CCG
PbR excluded: No

Background

If a person needs to take 2 antidiabetic drugs, canagliflozin is recommended as a possible treatment for people with type 2 diabetes when taken with a drug called metformin, only if the person:
• cannot take a type of drug called a sulfonylurea or
• is at significant risk of hypoglycaemia or its consequences.

If a person needs to take 3 antidiabetic drugs, canagliflozin is recommended as a possible treatment when taken with either metformin and a sulfonylurea, or metformin and a type of drug called a thiazolidinedione.
Canagliflozin is recommended as a possible treatment taken with insulin, with or without other antidiabetic drugs.
The LMMG recommends canagliflozin as the 2nd line ““gliflozin”” (1st line — dapagliflozin or empagliflozin).

Decisions of Lancashire local decision making groups:

NHS Blackburn With Darwen CCG and NHS East Lancashire CCG NHS Blackpool CCG NHS Chorley and South Ribble CCG and NHS Greater Preston CCG NHS Fylde and Wyre CCG NHS Morecambe Bay CCG NHS West Lancashire CCG

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