Medicines

Here you will find the recommendations we have made about the use of individual medicines in Lancashire.

Eluxadoline

Brand: Truberzi®
NICE TA: 471
Indication: Treating irritable bowel syndrome with diarrhoea (NICE TA471)
Disease category: Malignant Disease
Commissioning responsibility: CCG
PbR excluded: No

Background

Eluxadoline is recommended as an option for treating irritable bowel syndrome with diarrhoea in adults, only if:

•the condition has not responded to other pharmacological treatments (for example, antimotility agents, antispasmodics, tricyclic antidepressants) or

•pharmacological treatments are contraindicated or not tolerated, and

•it is started in secondary care.

Stop eluxadoline at 4 weeks if there is inadequate relief of the symptoms of irritable bowel syndrome with diarrhoea.

Decisions of Lancashire local decision making groups:

NHS Blackburn With Darwen CCG and NHS East Lancashire CCG NHS Blackpool CCG NHS Chorley and South Ribble CCG and NHS Greater Preston CCG NHS Fylde and Wyre CCG NHS Morecambe Bay CCG NHS West Lancashire CCG

Red

Red

Red

Red

Red

Red