Medicines

Here you will find the recommendations we have made about the use of individual medicines in Lancashire.

Opicapone

Brand: Ongentys ®
NICE TA: 
Indication: Parkinson’s disease – adjunctive therapy in adults with end-of-dose motor fluctuations who cannot be stabilised on preparations of levodopa/DOPA decarboxylase inhibitors
Disease category: Central nervous system
Commissioning responsibility: CCG
PbR excluded: No

Background

Opicapone is recommended as a second line catechol-o-methyltransferase [COMT] inhibitor in adult patients with Parkinson’s disease with “end of dose” motor fluctuations who cannot be stabilised on levodopa/DDCI inhibitors and who fail to respond to or are intolerant of entacapone, where tolcapone is being considered.

Recommendation

LMMG recommendation: Amber0
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Reason for decision:  Suitable for GP prescribing following recommendation/initiation by specialist

Supporting documents:

Opicapone Recommendation Oct18 (780.3 KiB)

Decisions of Lancashire local decision making groups:

NHS Blackburn With Darwen CCG and NHS East Lancashire CCG NHS Blackpool CCG NHS Chorley and South Ribble CCG and NHS Greater Preston CCG NHS Fylde and Wyre CCG NHS Morecambe Bay CCG NHS West Lancashire CCG

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