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Bempedoic acid with ezetimibe

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Nice TA:


Commissioning responsibility:


PbR excluded:


BNF chapter:
Cardiovascular system


1.1 Bempedoic acid with ezetimibe is recommended as an option for treating primary hypercholesterolaemia (heterozygous familial and non-familial) or mixed dyslipidaemia as an adjunct to diet in adults. It is recommended only if:

  • statins are contraindicated or not tolerated,

  • ezetimibe alone does not control low-density lipoprotein cholesterol well enough, and

  • the company provides bempedoic acid and bempedoic acid with ezetimibe according to the commercial arrangement.

Bempedoic acid with ezetimibe can be used as separate tablets or a fixed-dose combination.


LSCMMG Recommendation:

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Reason for decision:

Suitable for GP prescribing following recommendation/initiation by specialist

Supporting documents:

Decisions of Lancashire local decision making groups

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Last Updated: 14 - May - 2021