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Estradiol / micronised progesterone

Indication

Continuous combined hormone replacement therapy (HRT) for oestrogen deficiency symptoms in postmenopausal women with intact uterus and with at least 12 months since last menses

Green (Restricted)

Brand:

Bijuve

Nice TA:

Commissioning responsibility:

CCG

PbR excluded:

No

BNF chapter:
Endocrine system

Background

Estradiol (as estradiol hemihydrate) and progesterone 1mg/100mg Soft Capsules (Bijuve®) for continuous combined hormone replacement therapy (HRT) is recommended for initiation and ongoing prescribing in both primary and secondary care provided that:

    • Bijuve® is an alternative when other HRT treatments have not been tolerated or when Femoston-Conti® is being considered OR
    • Bijuve® replaces HRT regimens where separate oestrogen and micronised progesterone are used (single hormone products used in combination are more expensive than Bijuve®).

Recommendation

LSCMMG Recommendation:

Green (Restricted)

Reason for decision:

Suitable for initiation in primary care in line with restrictions

Supporting documents:

Decisions of Lancashire local decision making groups

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Last Updated: 31 - Aug - 2023