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Finasteride

Green

Brand:

Nice TA:

Commissioning responsibility:

CCG

PbR excluded:

No

BNF chapter:
Endocrine system

Background

Finasteride is the preferred 1st line 5α-reductase inhibitor for Benign Prostatic Hyperplasia (BPH) within the Lancashire ad South Cumbria Health Economies. This is because:
  • Finasteride is significantly less expensive than the alternative 5‑α reductase inhibitor dutasteride.
  • The Enlarged Prostate International Comparator Study (EPICS) found, when dutasteride or finasteride were administered for 12 months, they were similarly effective at 3 months and 12 months in reducing prostate volume, improving Qmax and urinary symptoms associated with BPH.
  • Additionally the EPICS study also found no difference in overall numbers of adverse events between finasteride and dutasteride.

Recommendation

LSCMMG Recommendation:

Green

Reason for decision:

Suitable for initiation in primary care

Supporting documents:

Decisions of Lancashire local decision making groups

Green
Pending
Green
Green
Pending
Green
Pending
Green
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Last Updated: 01 - Jul - 2016