Medicines

Here you will find the recommendations we have made about the use of individual medicines in Lancashire.

Dapagliflozin

Brand: Forxiga®
NICE TA: 597
Indication: Dapagliflozin with insulin for treating type 1 diabetes (NICE TA 597)
Disease category: Endocrine system
Commissioning responsibility: CCG
PbR excluded: No

Background

1.1 Dapagliflozin with insulin is recommended as an option for treating type 1 diabetes in adults with a body mass index (BMI) of at least 27 kg/m2 , when insulin alone does not provide adequate glycaemic control despite optimal insulin therapy, only if:
• they are on insulin doses of more than 0.5 units/kg of body weight/day and
• they have completed a structured education programme that is evidence based, quality assured, delivered by trained educators and includes information about diabetic ketoacidosis, such as:
• how to recognise its risk factors, signs and symptoms
• how and when to monitor blood ketone levels
• what actions to take for elevated blood ketones,
• and treatment is started and supervised by a consultant physician specialising in endocrinology and diabetes.

Recommendation

LMMG recommendation: Amber0
Click here to find the definitions for the colour classifications

Reason for decision:  Suitable for GP prescribing following recommendation/initiation by specialist

Supporting documents:

NICE TA597 - Dapagliflozin with insulin for treating type 1 diabetes

Decisions of Lancashire local decision making groups:

NHS Blackburn With Darwen CCG and NHS East Lancashire CCG NHS Blackpool CCG NHS Chorley and South Ribble CCG and NHS Greater Preston CCG NHS Fylde and Wyre CCG NHS Morecambe Bay CCG NHS West Lancashire CCG

Amber0

Amber0

Amber0

Amber0